Cyclodextrins tethered with oligolactides – green synthesis and structural assessment

• Cristian Peptu,
• Mihaela Balan-Porcarasu,
• Alena Šišková,
• Ľudovít Škultéty and
• Jaroslav Mosnáček

Beilstein J. Org. Chem. 2017, 13, 779–792, doi:10.3762/bjoc.13.77

• Virology, Biomedical Research Center Slovak Academy of Sciences, Dúbravská cesta 9, 84541 Bratislava, Slovakia 10.3762/bjoc.13.77 Abstract Biodegradable oligolactide derivatives based on α-, β- and γ-cyclodextrins (CDs) were synthesized by a green procedure in which CDs play the role of both the initiator

• low content of oligoester components were first prepared by a totally green procedure by Harada and co-workers [17]. They succeeded to polymerize a series of cyclic esters including β-butyrolactone (BL), δ-valerolactone (VL) and ε-caprolactone (CL). A recent work published by Galia et al. [18] brings

Contribution of microreactor technology and flow chemistry to the development of green and sustainable synthesis

• Flavio Fanelli,
• Giovanna Parisi,
• Leonardo Degennaro and
• Renzo Luisi

Beilstein J. Org. Chem. 2017, 13, 520–542, doi:10.3762/bjoc.13.51

• solvent, contributes to further validate the green procedure. The 2-MeTHF solutions of fluoroarenes 4 together with the hexane solution of n-BuLi were pumped into the flow system at −40 °C. The generated organozinc intermediate meets the solution of haloarenes and the catalyst, leading to the formation of

Selective and eco-friendly procedures for the synthesis of benzimidazole derivatives. The role of the Er(OTf)₃ catalyst in the reaction selectivity

• Natividad Herrera Cano,
• Jorge G. Uranga,
• Mónica Nardi,
• Antonio Procopio,
• Daniel A. Wunderlin and
• Ana N. Santiago

Beilstein J. Org. Chem. 2016, 12, 2410–2419, doi:10.3762/bjoc.12.235

• ) trifluoromethanesulfonate; green procedure; heterocycle; Introduction The formation of heterocyclic compounds is a very important task in organic synthesis, mainly because they are present in numerous biologically active compounds and in several natural products [1]. Among them the presence of benzimidazole [2][3][4][5][6

Oxidative phenylamination of 5-substituted 1-hydroxynaphthalenes to N-phenyl-1,4-naphthoquinone monoimines by air and light “on water”

• Julio Benites,
• Juan Meléndez,
• Cynthia Estela,
• David Ríos,
• Luis Espinoza,
• Iván Brito and
• Jaime A. Valderrama

Beilstein J. Org. Chem. 2014, 10, 2448–2452, doi:10.3762/bjoc.10.255

• concluded that singlet oxygen is involved in the oxidative amination reaction, albeit with partial contribution to the aerial oxidation processes. Conclusion In summary, we have developed a green procedure for the synthesis of N-phenyl-1,4-naphthoquinone monoimines, in moderate to excellent yields, from 5

Pd/C-catalyzed aerobic oxidative esterification of alcohols and aldehydes: a highly efficient microwave-assisted green protocol

• Marina Caporaso,
• Giancarlo Cravotto,
• Spyros Georgakopoulos,
• George Heropoulos,
• Katia Martina and
• Silvia Tagliapietra

Beilstein J. Org. Chem. 2014, 10, 1454–1461, doi:10.3762/bjoc.10.149

• enhanced by mild dielectric heating. Furthermore, it is a versatile green procedure which generally enables the isolation of esters to be carried out by simple filtration in almost quantitative yields. Keywords: aerobic oxidation; alcohol; esterification; heterogeneous catalysis; microwaves; Introduction